Global toxin review > Toxinology, TOXIC, POISON, VENOM

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Featured Articles

Viscoelastic and Electric Characteristics of Erythrocytes at Differenct Degrees of Hepatici Fibrosis

Modern hepatology knows a great number of etiological factors (hepatitis viruses, toxic effects including alcohol, autoimmune reactions, metabolic disturbances caused by ge-netic factors), the effect of which results in the development of chronic diffuse hepatic diseases. Toxic effects on liver are rather widespread, in most cases have a chronic character and result in the formation of fibrosis. In spite of the variety of pathogenetic mechanisms of effect on liver, the development and chronization of the processes of its damage are accompa-nied by systemic, similar in many respects, evolutionally established, unidirectional structural changes in the organ tissue. Go to download for rest of article.

Posted on October 26, 2007, 3:07 pm
Author: Vladimir Generalov, et al

PLATELET ACTIVE COMPONENTS FROM AGKISTRODON BLOMHOFFII USSURIENSIS SNAKE VENOM

Snake venoms have been reported to contain a number of platelet active components including enzymes and nonenzymatic proteins and peptides. Some of these factors induce platelet aggregation or activation, whereas others inhibit platelets aggregation.

Posted on July 21, 2007, 6:57 am
Author: Vitaliy Kabovskyy, University of Kiev

Snakes and spiders in Ukraine and Russia: envenoming and treatment

Every year there are more than two million envenoming victims in the world from contact with snakes and spiders bites. Nearly 3% of them result in death. Even though Europe has very little incedence of lethal lethal envenoming this region still has many acute cases. In our present work we will analyze the situation related to contact with snakes and spider in Ukraine and Russia and determine the availability of respective antiserums.

Posted on July 21, 2007, 6:41 am
Author: Vitaliy Kabovskyy, University of Kiev

IMMUNOPATHOGENIC PARALLELS OF FORMING THE OCCUPATIONAL NEUROINTOXICATIONS OF DIFFERENT ETIOLOGY

The Progradient process of occupational neurointoxications (chronic mercury intoxication and toxic encephalopathy, induced with the exposure to different substances of neurotropic effect) are accompanied by the system immunity disorder. The disturbance of lymphocyte activation process (the receptor density at the early (CD25) and late (CD95, HLA-DR) stages of lymphocyte activation is increased) was considered to be a common regularity of immunopathological process development at the background of the pronounced immunosuppression. Involving the autoimmune processes into the nervous system pathology development has been proofed. The new data about the immunopathogenesis of the diseases above are very important to search for the new measures of immunorehabilitation and may ground the involvement of immune corrective measures into the complex of treatment effects to prevent the diseases.

Posted on May 8, 2007, 4:12 am
Author: G.M. Bodienkova, V.S. Rukavishnikov, S.I. Kurcheve